Recombinant avian type i interferon

The present invention relates to a chicken interferon gene coding for the amino acid sequence of SEQ ID NO: 2. The present invention also relates to a method of producing chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes, a method of making a transgenic fow...

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Bibliographische Detailangaben
Hauptverfasser: FERRANDINO, ANTHONY F, SEKELLICK, MARGARET J, MARCUS, PHILIP I
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a chicken interferon gene coding for the amino acid sequence of SEQ ID NO: 2. The present invention also relates to a method of producing chicken interferon recombinantly, a method of isolating other non-mammalian interferon genes, a method of making a transgenic fowl having the chicken interferon gene incorporated therein, and method for delivery of the chicken interferon in the bird, such as by genetic immunization or aerosol. Expression of the chicken IFN gene yields functional chicken interferon.