Magnetic separation apparatus and methods employing an internal magnetic capture gradient and an external transport force

The present invention relates to apparatus and methods for separating, immobilizing, and quantifying biological substances from within a fluid medium. Biological substances are observed by employing a high internal gradient magnetic capture structure formed within a vessel, in conjunction with an ex...

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Bibliographische Detailangaben
Hauptverfasser: DOLAN, GERALD J, TERSTAPPEN, LEON W. M. M
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to apparatus and methods for separating, immobilizing, and quantifying biological substances from within a fluid medium. Biological substances are observed by employing a high internal gradient magnetic capture structure formed within a vessel, in conjunction with an externally-applied force for transporting magnetically responsive material toward the capture structure. The invention is also useful in conducting quantitative analysis and sample preparation in conjunction with automated cell enumeration techniques.