Expression of gene products from genetically manipulated strains of Bordetella

PCT No. PCT/CA96/00107 Sec. 371 Date Dec. 1, 1997 Sec. 102(e) Date Dec. 1, 1997 PCT Filed Feb. 23, 1996 PCT Pub. No. WO96/26282 PCT Pub. Date Aug. 29, 1996An expression system for expressing gene products from recombinant Bordetella strains and specific nucleic acid molecules useful in transforming...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	YACOOB, REZA K, LOOSMORE, SHEENA M, ZEALEY, GAVIN R, KLEIN, MICHEL H
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	PCT No. PCT/CA96/00107 Sec. 371 Date Dec. 1, 1997 Sec. 102(e) Date Dec. 1, 1997 PCT Filed Feb. 23, 1996 PCT Pub. No. WO96/26282 PCT Pub. Date Aug. 29, 1996An expression system for expressing gene products from recombinant Bordetella strains and specific nucleic acid molecules useful in transforming Bordetella strains for such expression are described. A nucleic acid molecule may comprise a Bordetella promoter operatively coupled to a heterologous gene encoding a non-Bordetella gene product with the heterologous gene transcriptionally regulated by the Bordetella promoter. The nucleic acid molecule may further comprise a further nucleic acid molecule encoding a leader sequence for secretion of the non-Bordetella gene product. Another nucleic acid molecule may comprise a Bordetella promoter coupled to a nucleic acid sequence encoding a non-Bordetella leader sequence for secretion of a gene product, which may be a Bordetella gene product or a non-Bordetella gene product.