Hydrazine derivative compounds as intermediates for preparing substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors

This invention relates to intermediate compounds which are useful for making substituted 1-phenyl-3-pyrazolecarboxamides. The compounds of the invention have the formula: in which: R'2 and R'3 each independently represent a hydrogen, a (C1-C6)alkyl, a (C3-C8)cycloalkyl, a (C3-C8)cycloalkyl...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GULLY, DANIELLE, LABEEUW, BERNARD, MOLIMARD, JEANARLES, BOIGEGRAIN, ROBERT, JEANJEAN, FRANCIS
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:This invention relates to intermediate compounds which are useful for making substituted 1-phenyl-3-pyrazolecarboxamides. The compounds of the invention have the formula: in which: R'2 and R'3 each independently represent a hydrogen, a (C1-C6)alkyl, a (C3-C8)cycloalkyl, a (C3-C8)cycloalkylmethyl; or R'2 and R'3 together constitute a trimethylene, tetramethylene or pentamethylene group; Ry is at position 4 or at position 5 and represents a group chosen from: cyano, carboxyl, (C1-C4)alkoxycarbonyl, benzyloxycarbonyl, sulpho, (C1-C4)alkylsulphonylamino, (C1-C4)alkylphenylsulphonylamino, carbamoyl, (C1-C4)alkylcarboxamido; on condition that R'2 and R'3 do not simultaneously represent hydrogen and on condition that R'2 is other than methyl when Ry is a sulpho group. The salts of the above compounds are also part of the invention.