14-EPI-19-nor-vitamin D compounds and methods

14-EPI-19-nor-vitamin D compounds and methods

19-nor-vitamin D analog compounds and a method of synthesizing such compounds are disclosed. More particularly, examples of such compounds include 14-epi-19-nor-1 alpha ,25-dihydroxyvitamin D3, 14-epi-20-epi-19-nor-1 alpha , 25-dihydroxyvitamin D3, 14-epi-20-epi-19-nor-1 alpha -hydroxyvitamin D3, 14...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PAAREN, HERBERT E
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:19-nor-vitamin D analog compounds and a method of synthesizing such compounds are disclosed. More particularly, examples of such compounds include 14-epi-19-nor-1 alpha ,25-dihydroxyvitamin D3, 14-epi-20-epi-19-nor-1 alpha , 25-dihydroxyvitamin D3, 14-epi-20-epi-19-nor-1 alpha -hydroxyvitamin D3, 14-epi-19-nor-1 alpha , 25-dihydroxyvitamin D2, 14-epi-19-nor-24-homo-1 alpha , 25-didydroxyvitamin D3, 14-epi-19-nor-20(S)-hydroxymethyl-1 alpha -hydropregnacalciferol, and 14-epi-19-nor-20(R)-hydroxymethyl-1 alpha -hydroxypregnacalciferol.