Recombinant human interleukin-1 alpha

The invention relates to the cloning of the human IL-1 gene, its engineering into suitable expression vectors, transformation of host organisms with such expression vectors and production of biologically active recombinant human IL-1 by culture of such transformed cells. Additionally, the invention...

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Bibliographische Detailangaben
Hauptverfasser: LOMEDICO, PETER T, MIZEL, STEVEN B, GUBLER, ULRICH A
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to the cloning of the human IL-1 gene, its engineering into suitable expression vectors, transformation of host organisms with such expression vectors and production of biologically active recombinant human IL-1 by culture of such transformed cells. Additionally, the invention relates to the isolation and use of the resulting recombinant human IL-1 polypeptides.