Cyclic peptides containing Arg-Gly-Asp, and derivatives thereof, as adhesion inhibitors
The invention relates to novel cyclopeptides of the formula Icyclo-(Arg-B-Asp-D-E)Iin which B, D, and E have the meanings defined herein, and their salts. These compounds act as integrin inhibitors and can be used, in particular, for the prophylaxis and treatment of disorders of the circulation and...
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| creator | KESSLER HORST WERMUTH JOCHEN HOLZEMANN GUENTER RIPPMANN FRIEDRICH DIEFENBACH BEATE HAUBNER ROLAND FELDING-HABERMANN BRUNHILDE JONCZYK ALFRED |
| description | The invention relates to novel cyclopeptides of the formula Icyclo-(Arg-B-Asp-D-E)Iin which B, D, and E have the meanings defined herein, and their salts. These compounds act as integrin inhibitors and can be used, in particular, for the prophylaxis and treatment of disorders of the circulation and in tumor therapy. |
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These compounds act as integrin inhibitors and can be used, in particular, for the prophylaxis and treatment of disorders of the circulation and in tumor therapy.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Cyclic peptides containing Arg-Gly-Asp, and derivatives thereof, as adhesion inhibitors |
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