Peptide derivatives of alpha-MSH and their application

Peptide derivatives of alpha-MSH and their application

PCT No. PCT/FR94/01108 Sec. 371 Date May 22, 1995 Sec. 102(e) Date May 22, 1995 PCT Filed Sep. 22, 1994 PCT Pub. No. WO95/08564 PCT Pub. Date May 30, 1995Provided is a compound containing a peptide of at least 4 amino acids including the following sequence: His Phe* Arg, wherein Phe* represents phen...

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Hauptverfasser: D'HINTERLAND, LUCIEN DUSSOURD, PINEL, ANNE-MARIE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Zusammenfassung:PCT No. PCT/FR94/01108 Sec. 371 Date May 22, 1995 Sec. 102(e) Date May 22, 1995 PCT Filed Sep. 22, 1994 PCT Pub. No. WO95/08564 PCT Pub. Date May 30, 1995Provided is a compound containing a peptide of at least 4 amino acids including the following sequence: His Phe* Arg, wherein Phe* represents phenylalanine or a halogenated derivative of phenylalanine the said peptide being conjugated with thioctic acid, dihydrolioic acid, or N-lipoyl-lysine, in the form of the corresponding salts, esters or amides. In particular, compounds with anti-allergic and anti-inflammatory activities on the one had, and melanogenesis-activating activities on the other, are described.