Nucleic acid hybridization based assay for determining a substance of interest

The application describes homogeneous assays for determining ligands. A sample is contacted with a labeled substance P2 and receptor R. The receptor R consists of one molecule of P1, which monovalently and specifically binds to P2, and one molecule for R1, which binds to the ligand of interest. Comp...

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Bibliographische Detailangaben
Hauptverfasser:	DEGER, ARNO, SCHENK, ROLAND
Format:	Patent
Sprache:	eng
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The application describes homogeneous assays for determining ligands. A sample is contacted with a labeled substance P2 and receptor R. The receptor R consists of one molecule of P1, which monovalently and specifically binds to P2, and one molecule for R1, which binds to the ligand of interest. Complexes of P1, P2, R1 and ligand form, and are determined. R1 must be a nucleic acid molecule.