Triazole antifungal agents

The invention provides antifungal compounds of the formula: (I) and pharmaceutically acceptable salts thereof, whereinR is phenyl substituted by 1 to 3 substituents each independently selected from halo, -CF3 and -OCF3; R1 is C1-C4 alkyl; R2 is H or C1-C4 alkyl; X is CH or N; and Y is F or Cl. The i...

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Bibliographische Detailangaben
Hauptverfasser:	RICHARDSON, KENNETH, RAY, STEPHEN J
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides antifungal compounds of the formula: (I) and pharmaceutically acceptable salts thereof, whereinR is phenyl substituted by 1 to 3 substituents each independently selected from halo, -CF3 and -OCF3; R1 is C1-C4 alkyl; R2 is H or C1-C4 alkyl; X is CH or N; and Y is F or Cl. The invention provides antifungal compounds of the formula: (I) and pharmaceutically acceptable salts thereof, whereinR is phenyl substituted by 1 to 3 substituents each independently selected from halo, -CF3 and -OCF3; R1 is C1-C4 alkyl; R2 is H or C1-C4 alkyl; X is CH or N; and Y is F or Cl.