Long-chain alkylamides of amino acids and peptides with anti-proliferative and anti-inflammatory properties

Long-chain alkylamides of amino acids and peptides with anti-proliferative and anti-inflammatory properties

Long-chain, unbranched alkylamides of the general formulaCH3-(CH2)nN-NH-Rin which n=11-20 and R=amino acid, its D- and L-enantiomers, di- and tripeptides, forms derived by N-protective groups, and terminal ethyl esters as well as its physiologically compatible salt forms as active pharmaceutical sub...

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Bibliographische Detailangaben
Hauptverfasser: ENGEL, JUERGEN, VOEGELI, RAINER, KUTSCHER, BERNHARD, BERND, MICHAEL, GROSSMANN, HEINZ, KICK, MARIA, LIEFLAENDER, MANFRED, ARP
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Long-chain, unbranched alkylamides of the general formulaCH3-(CH2)nN-NH-Rin which n=11-20 and R=amino acid, its D- and L-enantiomers, di- and tripeptides, forms derived by N-protective groups, and terminal ethyl esters as well as its physiologically compatible salt forms as active pharmaceutical substances with anti-proliferative and anti-inflammatory properties.