Antibodies to G protein coupled glutamate receptors

Mammalian G protein coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereby may be used to identify agonists and antagonists of G protein coupled glutamate receptor mediated...

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Hauptverfasser: MULVIHILL, EILEEN RANAE, HAGEN, FREDERICK STAMNER, ALMERS, WOLARD, HOUAMED, KHALED M
Format: Patent
Sprache:eng
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Zusammenfassung:Mammalian G protein coupled glutamate receptors are identified, isolated and purified. The receptors have been cloned, sequenced and expressed by recombinant means. The receptors and antibodies thereby may be used to identify agonists and antagonists of G protein coupled glutamate receptor mediated neuronal excitation, as well as in methods of diagnosis.