Syn-isomer of thiazolyl intermediate and process for the preparation thereof

The present invention provides a stable, crystalline syn-isomer of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetyl chloride hydrochloride substantially free of the anti-isomer and a process for the preparation thereof which may be used in an acylation process for the preparation of useful broad-spectr...

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Bibliographische Detailangaben
Hauptverfasser: ROUBIE, JOHN M, LIM, GARY M. F
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a stable, crystalline syn-isomer of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetyl chloride hydrochloride substantially free of the anti-isomer and a process for the preparation thereof which may be used in an acylation process for the preparation of useful broad-spectrum antibiotics.