Cyclic peptide antifungal agents

Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I I wherein: R', R'', R''', Rx1, Rx2, Ry1, Ry2, Ry3, Ry4, and R0 are as defined herein below; R2 is a novel acyl side chain. Also provided are n...

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Bibliographische Detailangaben
Hauptverfasser:	HENLE, STACY KAY, TURNER, WILLIAM WILSON
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I I wherein: R', R'', R''', Rx1, Rx2, Ry1, Ry2, Ry3, Ry4, and R0 are as defined herein below; R2 is a novel acyl side chain. Also provided are novel formulations and methods of inhibiting fungal and parasitic activity.