Process for preparing daunorubicin

The ability to improve the conversion of epsilon -rhodomycinone to daunorubicin can be conferred on a bacterial host transformed with a recombinant vector comprising a DNA coding for an appropriate protein useful for that conversion. Furthermore, the bacterial host may have a mutation that blocks th...

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Bibliographische Detailangaben
Hauptverfasser: FILIPPINI, SILVIA, COLOMBO, ANNA LUISA, SCOTTI, CLAUDIO, HUTCHINSON, CHARLES RICHARD
Format: Patent
Sprache:eng
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Zusammenfassung:The ability to improve the conversion of epsilon -rhodomycinone to daunorubicin can be conferred on a bacterial host transformed with a recombinant vector comprising a DNA coding for an appropriate protein useful for that conversion. Furthermore, the bacterial host may have a mutation that blocks the function of a gene of daunorubicin metabolism.