Hammerhead ribozymes for preferred targets

A method for selecting a hammerhead ribozyme target site comprising the step of selecting a site comprising an XXUH/XX nucleotide sequence, where XX are strong duplex forming bases, H is U, A or C, and the slash represents the cleavage site.

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Bibliographische Detailangaben
Hauptverfasser:	SWIGGEN, JAMES A, MAMONE, J. ANTHONY
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A method for selecting a hammerhead ribozyme target site comprising the step of selecting a site comprising an XXUH/XX nucleotide sequence, where XX are strong duplex forming bases, H is U, A or C, and the slash represents the cleavage site.