Dihydropyridinecarboxylic acid anhydrides

The invention relates to the compounds of formula I (I) wherein R is lower alkyl or hydrogen; R1 is hydrogen, lower alkyl or aryl-lower alkyl; R2 is hydrogen, nitro, cyano trifluoromethyl, halo, lower alkoxy, lower alkyl, lower alkoxycarbonyl, aminocarbonyl or mono- or di-lower alkylaminocarbonyl, a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MUGRAGE, BENJAMIN B
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the compounds of formula I (I) wherein R is lower alkyl or hydrogen; R1 is hydrogen, lower alkyl or aryl-lower alkyl; R2 is hydrogen, nitro, cyano trifluoromethyl, halo, lower alkoxy, lower alkyl, lower alkoxycarbonyl, aminocarbonyl or mono- or di-lower alkylaminocarbonyl, amino or mono- or di-lower alkylamino; and pharmaceutically acceptable salts thereof when R1 is hydrogen; which are useful as endothelin antagonists. The invention relates to the compounds of formula I (I) wherein R is lower alkyl or hydrogen; R1 is hydrogen, lower alkyl or aryl-lower alkyl; R2 is hydrogen, nitro, cyano trifluoromethyl, halo, lower alkoxy, lower alkyl, lower alkoxycarbonyl, aminocarbonyl or mono- or di-lower alkylaminocarbonyl, amino or mono- or di-lower alkylamino; and pharmaceutically acceptable salts thereof when R1 is hydrogen; which are useful as endothelin antagonists.