5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use
An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen,...
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| creator | MOR+E,ACU A+EE N MOSET MARINA CASTELLANO BERLANGA JOS+E,ACU E+EE M SCHLICK ERICH BRA+E,OTL N+EE A MIGUEL F KEILHAUER GERHARD |
| description | An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-acyl, C2--C7-alkoxycarbonyl, ureyl, aminocarbonyl or C2-C7-alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described.
An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-acyl, C2--C7-alkoxycarbonyl, ureyl, aminocarbonyl or C2-C7-alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described. |
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An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-acyl, C2--C7-alkoxycarbonyl, ureyl, aminocarbonyl or C2-C7-alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described.</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960903&DB=EPODOC&CC=US&NR=5552544A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960903&DB=EPODOC&CC=US&NR=5552544A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOR+E,ACU A+EE N MOSET; MARINA</creatorcontrib><creatorcontrib>CASTELLANO BERLANGA; JOS+E,ACU E+EE M</creatorcontrib><creatorcontrib>SCHLICK; ERICH</creatorcontrib><creatorcontrib>BRA+E,OTL N+EE A; MIGUEL F</creatorcontrib><creatorcontrib>KEILHAUER; GERHARD</creatorcontrib><title>5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use</title><description>An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-acyl, C2--C7-alkoxycarbonyl, ureyl, aminocarbonyl or C2-C7-alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described.
An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-acyl, C2--C7-alkoxycarbonyl, ureyl, aminocarbonyl or C2-C7-alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHA31c3LLCnKT0rNq8qPTkmNzSzOLyzNzMvPycxL1TXUMdZNyczPSy1WKMlIzSxSKChKLUgsSiwBiikk5qVARUuLU3kYWNMSc4pTeaE0N4O8m2uIs4duakF-fGpxQWJyal5qSXxosKmpqZGpiYmjMWEVAKjhM0k</recordid><startdate>19960903</startdate><enddate>19960903</enddate><creator>MOR+E,ACU A+EE N MOSET; MARINA</creator><creator>CASTELLANO BERLANGA; JOS+E,ACU E+EE M</creator><creator>SCHLICK; ERICH</creator><creator>BRA+E,OTL N+EE A; MIGUEL F</creator><creator>KEILHAUER; GERHARD</creator><scope>EVB</scope></search><sort><creationdate>19960903</creationdate><title>5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use</title><author>MOR+E,ACU A+EE N MOSET; MARINA ; CASTELLANO BERLANGA; JOS+E,ACU E+EE M ; SCHLICK; ERICH ; BRA+E,OTL N+EE A; MIGUEL F ; KEILHAUER; GERHARD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US5552544A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1996</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MOR+E,ACU A+EE N MOSET; MARINA</creatorcontrib><creatorcontrib>CASTELLANO BERLANGA; JOS+E,ACU E+EE M</creatorcontrib><creatorcontrib>SCHLICK; ERICH</creatorcontrib><creatorcontrib>BRA+E,OTL N+EE A; MIGUEL F</creatorcontrib><creatorcontrib>KEILHAUER; GERHARD</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MOR+E,ACU A+EE N MOSET; MARINA</au><au>CASTELLANO BERLANGA; JOS+E,ACU E+EE M</au><au>SCHLICK; ERICH</au><au>BRA+E,OTL N+EE A; MIGUEL F</au><au>KEILHAUER; GERHARD</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use</title><date>1996-09-03</date><risdate>1996</risdate><abstract>An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-acyl, C2--C7-alkoxycarbonyl, ureyl, aminocarbonyl or C2-C7-alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described.
An antitumor 5-nitrobenzo[de]isoquinoline-1,3-dione of the formula I I where n is 1 or 2, R1 and R2 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-hydroxyalkyl, pyrrolidinyl, morpholino, piperidinyl or piperacinyl and R3 and R4 are identical or different and are each hydrogen, C1-C6-alkyl, C1-C6-acyl, C2--C7-alkoxycarbonyl, ureyl, aminocarbonyl or C2-C7-alkylaminocarbonyl, and its salts with physiologically tolerated acids, are described.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 5-nitrobenzo[de]isoquinoline-1,3-diones their preparation and their use |
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