42-Epi-rapamycin and pharmaceutical compositions thereof

This invention comprises the compound of 42-Epimer Rapamycin of the following structural formula: as well as pharmaceutical compositions containing 42-Epi-Rapamycin and its use in methods for inducing immunosuppression and methods for treating transplantation rejection, graft vs. host disease, autoi...

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Bibliographische Detailangaben
Hauptverfasser: GRINFELD, ALEXANDER A, CAUFIELD, CRAIG E
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention comprises the compound of 42-Epimer Rapamycin of the following structural formula: as well as pharmaceutical compositions containing 42-Epi-Rapamycin and its use in methods for inducing immunosuppression and methods for treating transplantation rejection, graft vs. host disease, autoimmune diseases, diseases of inflammation, solid tumors, fungal infections, adult T-cell leukemia/lymphomas and hyperproliferative vascular disorders. This invention comprises the compound of 42-Epimer Rapamycin of the following structural formula: as well as pharmaceutical compositions containing 42-Epi-Rapamycin and its use in methods for inducing immunosuppression and methods for treating transplantation rejection, graft vs. host disease, autoimmune diseases, diseases of inflammation, solid tumors, fungal infections, adult T-cell leukemia/lymphomas and hyperproliferative vascular disorders.