Platinum complexes

Pt(IV) complexes of formula I, I where X is halide, pseudohalide or OH, R1 and R2 are H, C1 to C6 alkyl, cycloalkyl, aryl or R1NH2 is a heterocyclic hydrogen donor, and may be the same or different, R3 and R4 are H, C1 to C5 alkyl, cycloalkyl or aryl and may be the same or different, and R5 is H, Me...

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Bibliographische Detailangaben
Hauptverfasser:	BARNARD, CHRISTOPHER F. J, BOSSARD, GERALD E
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Pt(IV) complexes of formula I, I where X is halide, pseudohalide or OH, R1 and R2 are H, C1 to C6 alkyl, cycloalkyl, aryl or R1NH2 is a heterocyclic hydrogen donor, and may be the same or different, R3 and R4 are H, C1 to C5 alkyl, cycloalkyl or aryl and may be the same or different, and R5 is H, Me or Et, have activity in vitro and in vivo against cancer cells.