In vitro inhibition of the HIV virus with ionic tungstoniobate compounds

In vitro inhibition of the HIV virus with ionic tungstoniobate compounds

PCT No. PCT/GB91/02101 Sec. 371 Date Aug. 26, 1993 Sec. 102(e) Date Aug. 26, 1993 PCT Filed Nov. 27, 1991 PCT Pub. No. WO92/09292 PCT Pub. Date Jun. 11, 1992.Tungstoniobate compounds containing an ion of general formula [Ax Wy Nba Ob]p-I where A=P, Si, Ge, x=0 or an integer from 1 to 10, y is an int...

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Hauptverfasser: ABRAMS, MICHAEL J, HILL, CRAIG L, SCHINAZI, RAYMOND F, THEOBALD, BRIAN R. C, BOSSARD, GERALD E
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:PCT No. PCT/GB91/02101 Sec. 371 Date Aug. 26, 1993 Sec. 102(e) Date Aug. 26, 1993 PCT Filed Nov. 27, 1991 PCT Pub. No. WO92/09292 PCT Pub. Date Jun. 11, 1992.Tungstoniobate compounds containing an ion of general formula [Ax Wy Nba Ob]p-I where A=P, Si, Ge, x=0 or an integer from 1 to 10, y is an integer from 1 to 10, y is an integer from 1 to 40, a is an integer from 1 to 8, b is an integer from 15 to 150, and p is an integer dependent upon the nature and oxidation state of element A, have been found to be active against viruses including especially HIV and Herpes Simplex. Pharmaceutical compositions and methods of treatment are disclosed.