Pharmaceutical methods of using heterocyclic derivatives of N-phenylamides

Pharmaceutical methods of using heterocyclic derivatives of N-phenylamides

New central nervous system agents conform to formula I: (I) wherein R=H or C1-4 alkoxy; X=CH or N; Y=NH, O or S; Z=C1-4 alkyl, C3-6 cycloalkyl, C2-3 alkenyl, NH2, C1-4 alkylamino, or C1-4 alkoxyalkyl, with the proviso that Z may not be CH3 when R=H, X=CH, and Y=NH and Z may not be CH3 when R=H, X=N...

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Bibliographische Detailangaben
Hauptverfasser: ORTIZ, ASTRID A, WATSON, BRETT T
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:New central nervous system agents conform to formula I: (I) wherein R=H or C1-4 alkoxy; X=CH or N; Y=NH, O or S; Z=C1-4 alkyl, C3-6 cycloalkyl, C2-3 alkenyl, NH2, C1-4 alkylamino, or C1-4 alkoxyalkyl, with the proviso that Z may not be CH3 when R=H, X=CH, and Y=NH and Z may not be CH3 when R=H, X=N and Y=NH and NHC(O)Z is in the para- position.