Co-administration of S-adenosyl-L-methionine to reduce the nephrotoxicity of cisplatin therapy

Co-administration of S-adenosyl-L-methionine to reduce the nephrotoxicity of cisplatin therapy

PCT No. PCT/JP93/01250 Sec. 371 Date Apr. 7, 1994 Sec. 102(e) Date Apr. 7, 1994 PCT Filed Sep. 3, 1993 PCT Pub. No. WO94/05299 PCT Pub. Date Mar. 17, 1994.A pharmaceutical composition for use as a nephrotoxicity alleviator for alleviating the nephrotoxicity caused by a drug administered into the liv...

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Bibliographische Detailangaben
Hauptverfasser: KAWABATA, HIRONORI, ENDO, TAKESHI, MORIGUCHI, KOEI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Zusammenfassung:PCT No. PCT/JP93/01250 Sec. 371 Date Apr. 7, 1994 Sec. 102(e) Date Apr. 7, 1994 PCT Filed Sep. 3, 1993 PCT Pub. No. WO94/05299 PCT Pub. Date Mar. 17, 1994.A pharmaceutical composition for use as a nephrotoxicity alleviator for alleviating the nephrotoxicity caused by a drug administered into the living organism, which composition contains S-adenosyl-L-methionine or a salt thereof as an active ingredient is provided. Also provided is a pharmaceutical composition for use as an agent for potentiating the antitumor activity of platinum complex compounds, which composition contains S-adenosyl-L-methionine as an active ingredient.