Method for the suppression of an immune response with antigen-MPEG conjugates in nonsensitized individuals

A method for suppressing the capacity of a mammal to mount an immune response which would be caused by the administration of one or more biologically active foreign proteins, comprising the administration of an immunosuppressively effective amount of a tolerogen corresponding to the foreign protein...

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Bibliographische Detailangaben
Hauptverfasser: LANG, GLEN M, SEHON, ALEC
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A method for suppressing the capacity of a mammal to mount an immune response which would be caused by the administration of one or more biologically active foreign proteins, comprising the administration of an immunosuppressively effective amount of a tolerogen corresponding to the foreign protein or proteins conjugated to mono methoxy (polyethylene glycol), administration being performed prior to the administration of the protein or proteins.