N-acyl-4-phenyl-pyrrolidin-2-ones and method for preparing

The invention is directed to N-acetyl-4-phenyl-pyrrolidin-2-ones, which, because of their pronounced cerebroprotective effect in human medicine, can be used for the prophylaxis and treatment of cerebral functional disorders. Pursuant to the invention, these compounds are synthesized by reacting 4-ph...

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Bibliographische Detailangaben
Hauptverfasser:	SEREDENIN, SERGEJ B, VORONINA, TATJANA A, ROSTOCK, ANGELIKA, MESCERJAKOVA, LARISA M, SIEGEMUND, CHRISTINE, ROZANCEV, GRIGORIJ G, GARIBOVA, TAISIJA L, LOHMANN, DIETER, GLOZMAN, OLEG M, ZMURENKO, LJUDMILA A, VALDMAN, ARTUR V, ZENKER, LOTHAR, RACHMANKULOVA, ILMIRA C, WUNDERLICH, HELMUT
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention is directed to N-acetyl-4-phenyl-pyrrolidin-2-ones, which, because of their pronounced cerebroprotective effect in human medicine, can be used for the prophylaxis and treatment of cerebral functional disorders. Pursuant to the invention, these compounds are synthesized by reacting 4-phenyl-pyrrolidin-2-ones with a reactive derivative of a carboxylic acid, or by cyclizing N-acylaminobutyric acid derivatives.