Quinoline derivative fumarates

Quinoline derivative fumarates

Compounds having an activity to stimulate the carcinostatic effect of carcinostatic agents, which can be expressed by the following general formula (1): (1) in which A is (in which R1, R2 and R3 are each independent and represent a hydrogen atom or a phenyl group) are made into fumarates so as to im...

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Bibliographische Detailangaben
Hauptverfasser: OTSUKA, KENGO, YANO, OSAMU, FUKAZAWA, NOBUYUKI, IWATA, DAIJI, KAWAI, YUKICHI, SUZUKI, TUNEJI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds having an activity to stimulate the carcinostatic effect of carcinostatic agents, which can be expressed by the following general formula (1): (1) in which A is (in which R1, R2 and R3 are each independent and represent a hydrogen atom or a phenyl group) are made into fumarates so as to improve their oral absorbability and solubility in water without interfering with their effects.