DNA's encoding signal peptides

Novel signal peptides capable of functioning in yeasts have the amino acid sequence: Met-A1-A2-X-B-C-D-E-F wherein A1 is a peptide chain composed of 1-3 amino acids each selected from the group consisting of Arg, Ser, Lys and His, A2 is a peptide chain composed of 1-3 amino acids, X is a peptide cha...

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Bibliographische Detailangaben
Hauptverfasser:	KAWABE, HARUHIDE, KOBAYASHI, KAORU, HAYASUKE, NAOFUMI, MASAKI, ATSUSHI, OKABAYASHI, KEN, ISHIDA, YUTAKA, TSUTSUI, KIYOSHI, MINAMINO, HITOSHI, IKEGAYA, KAZUO, UEDA, SADAO, NAKAGAWA, YUKIMITSU, MURAKAMI, KOHJI
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Novel signal peptides capable of functioning in yeasts have the amino acid sequence: Met-A1-A2-X-B-C-D-E-F wherein A1 is a peptide chain composed of 1-3 amino acids each selected from the group consisting of Arg, Ser, Lys and His, A2 is a peptide chain composed of 1-3 amino acids, X is a peptide chain composed of 8-10 hydrophobic amino acids, B is Pro or Ser, C is Gly or Pro, D Cys, Ala, Leu, Ser, Thr and Val, E is Trp or Gln and F is Ala or Gly. DNA sequences coding for these signal peptides can be used for the secretory expression of heterologous proteins in yeasts.