Melt granulated compositions for preparing sustained release dosage forms

Therapeutically active sustained release dosage forms are described which are prepared from compositions which comprise (A) a hydrophilic cellulose ether polymer or mixtures thereof as a binder matrix material, (B) a granulating medium selected from the group consisting of a lipid component, polyethylene glycol polymers, and mixtures thereof, said granulating medium having a melting range higher than about 30 DEG C., and (C) a therapeutically active medicament, said components being in melt association. The compositions are prepared by a melt granulation process.