N-cyanoamidine derivatives as anti-influenza agents

N-cyanoamidine derivatives as anti-influenza agents

Antiinfluenza A activity was found in compounds of the formula: wherein: X is 2-phenylethyl, 2-furanylmethyl, or where one of R1 and R2 is H and the other is phenylamino; Z is -SCH3 when X is or when X is 2-phenylethyl or 2-furanylmethyl; or a pharmaceutically acceptable salt thereof. Antiinfluenza...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: LUBECK, MICHAEL D, JAGDMANN, GUNNAR E, UWAYDAH, IBRAHIM M, MUNSON, JR., HARRY R, DAVIS, ALAN R, HSU, KUO-HOM L, TELLER, DANIEL M
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Antiinfluenza A activity was found in compounds of the formula: wherein: X is 2-phenylethyl, 2-furanylmethyl, or where one of R1 and R2 is H and the other is phenylamino; Z is -SCH3 when X is or when X is 2-phenylethyl or 2-furanylmethyl; or a pharmaceutically acceptable salt thereof. Antiinfluenza A activity was found in compounds of the formula: wherein: X is 2-phenylethyl, 2-furanylmethyl, or where one of R1 and R2 is H and the other is phenylamino; Z is -SCH3 when X is or when X is 2-phenylethyl or 2-furanylmethyl; or a pharmaceutically acceptable salt thereof.