Method for immunological assay of free lipoprotein associated coagulation inhibitor (LACI) and kit therefor

In methods for immunologically assaying free lipoprotein associated coagulation inhibitor (hereafter abbreviated as "LACI") in a human inspection sample using a first antibody immobilized on an insoluble carrier and a labeled second antibody, a method for immunological assay of free LACI a...

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Hauptverfasser: KOIKE, YUKIYA, SUZUKI, KOJI, ICHIKAWA, YATARO
Format: Patent
Sprache:eng
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Zusammenfassung:In methods for immunologically assaying free lipoprotein associated coagulation inhibitor (hereafter abbreviated as "LACI") in a human inspection sample using a first antibody immobilized on an insoluble carrier and a labeled second antibody, a method for immunological assay of free LACI and a kit therefor wherein (i) any one antibody of the first antibody and the second antibody is a monoclonal antibody recognizing the polypeptide (K3) of the following amino sequence LeuThrProAlaAspArgGlyLeuCysArg AlaAsnGluAsnArgPheTyrTyrAsnSer Val (hereafter referred to as a "K3-antibody"), and (ii) the other antibody is a monoclonal antibody recognizing the polypeptide (K1) of the following amino acid sequence AlaPheLysAlaAspAsp GlyProCysLysAlaIle MetLysArgPhePhePhe AsnIlePhe (hereafter referred to as a "K1-antibody").