Preparation of 2-(3-oxoalk(en)yl)-3-isothiazolones and derivatives

Antimicrobial compounds of the formula I or II wherein R is hydrogen, halogen, or (C1-C4)alkyl group; R1 is hydrogen or halogen; alternatively, R and R1 may be taken together with the carbons to which they are attached to form a 5- to 7-membered carbocyclic ring, said ring optionally being aromatic;...

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Hauptverfasser: OSEI-GYIMAH, PETER, LANGE, BARRY C
Format: Patent
Sprache:eng
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Zusammenfassung:Antimicrobial compounds of the formula I or II wherein R is hydrogen, halogen, or (C1-C4)alkyl group; R1 is hydrogen or halogen; alternatively, R and R1 may be taken together with the carbons to which they are attached to form a 5- to 7-membered carbocyclic ring, said ring optionally being aromatic; R2 is hydrogen or (C1-C3)alkyl group; and R3 is hydrogen, substituted or unsubstituted (C1-C18)alkyl, substituted or unsubstituted (C2-C18)alkenyl, substituted or unsubstituted (C2-C18)alkynyl, substituted or unsubstituted (C4-C8)cycloalkyl or cycloalkenyl, substituted or unsubstituted (C6-C10)aryl or arylalkyl group are disclosed. Antimicrobial compounds of the formula I or II wherein R is hydrogen, halogen, or (C1-C4)alkyl group; R1 is hydrogen or halogen; alternatively, R and R1 may be taken together with the carbons to which they are attached to form a 5- to 7-membered carbocyclic ring, said ring optionally being aromatic; R2 is hydrogen or (C1-C3)alkyl group; and R3 is hydrogen, substituted or unsubstituted (C1-C18)alkyl, substituted or unsubstituted (C2-C18)alkenyl, substituted or unsubstituted (C2-C18)alkynyl, substituted or unsubstituted (C4-C8)cycloalkyl or cycloalkenyl, substituted or unsubstituted (C6-C10)aryl or arylalkyl group are disclosed.