Naphthalene derivatives

The present invention concerns naphthalene derivatives of the formula: with specific meanings for the substituents R to R and Y and Z. The above compounds are useful as medicaments for the treating of diseases resulting in an increased production of prostaglandin or leukotrines, for treating an infl...

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Hauptverfasser: HARADA, KOUKICHI, SHIMOMURA, NAOYUKI, KUSUBE, KENICHI, OKANO, KAZUO, MIYAZAWA, SHUHEI, CLARK, RICHARD S. J, CHIBA, SUZUKI, TAKESHI, YOSHIMURA, HIROYUKI, KAWAHARA, TETSUYA, MORI, TAKASHI, MURAMOTO, KENZO, HORIE, TORU, ABE, SHINYA, YAMATSU, ISAO, HASHIDA, RYOICHI, SHIROTA, HIROSHI, INOUE
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention concerns naphthalene derivatives of the formula: with specific meanings for the substituents R to R and Y and Z. The above compounds are useful as medicaments for the treating of diseases resulting in an increased production of prostaglandin or leukotrines, for treating an inflammatory disease and for treating a disease selected from chronic rheumatoid arthritis, osteoarthritis, shoulder periarthritis, cervicobrachial syndrome and lumbago.