Method of making antibodies to antigenic epitopes of IGE present on B cells but not basophil cell surface or secreted, soluble IGE

A method for producing antibodies specific for antigenic associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane is disclosed. The epitopes recognized by the antibodies of the invention are present on IgE-bearing B cells but not basophils or in th...

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Sprache:eng
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Zusammenfassung:A method for producing antibodies specific for antigenic associated with the extracellular segment of the domain which anchors immunoglobulins to the B cell membrane is disclosed. The epitopes recognized by the antibodies of the invention are present on IgE-bearing B cells but not basophils or in the secreted, soluble form of IgE.