Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
The invention relates to a process for the preparation of highly antibacterially active enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids and derivatives of the formula (I) (I) in which 1) a compound of the formula is reacted with a compound of the formula (6) to form a compound of th...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The invention relates to a process for the preparation of highly antibacterially active enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids and derivatives of the formula (I) (I) in which 1) a compound of the formula is reacted with a compound of the formula (6) to form a compound of the formula followed by cyclization to form a compound of the formula and further cyclization to form a compound of the formula (9) an finally reaction of the cyclized product with amines of the formula |
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