THERAPEUTIC POLYAMINE-AMIDES

A compound of formula I optionally in the form of an acid addition salt in which formula: A represents a substituent which is: hydroxyl, O-alkyl, O-cycloalkyl, O-alkenyl, O-aryl, O-aralkyl, O-carbamate, O-carbonate, O-acyl or halogen a is O-5; the substituents A are identical or different when a is...

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Bibliographische Detailangaben
Hauptverfasser: USHERWOOD, PETER N. R, BLAGBROUGH, IAN S, MATHER, ALAN J, BYCROFT, BARRIE W
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A compound of formula I optionally in the form of an acid addition salt in which formula: A represents a substituent which is: hydroxyl, O-alkyl, O-cycloalkyl, O-alkenyl, O-aryl, O-aralkyl, O-carbamate, O-carbonate, O-acyl or halogen a is O-5; the substituents A are identical or different when a is more than 1; B represents a C1-C6 aliphatic hydrocarbon group optionally carrying one or more of the substituents: hydroxyl, amino, halogen, C1-C4 alkoxy, C1-C4 alkyl, aryloxy or carboalkoxy and optionally comprising one or more sites of unsaturatlon and/or one or more carbonyl groups or ketal derivatives thereof; b is O or 1; c, d, f and h, which may be identical or different, are 2, 3, 4, 5 or 6; and i is 0 or 1 D, E and F, which may be identical or different, represent hydrogen or C1-C4 alkyl or cycloalkyl, and G and J which may be identical or different represent hydrogen, alkyl or cycloalkyl or G and J together with the nitrogen atom to which they are attached represent a saturated heterocyclic ring system.