Tricyclic glycinamide derivatives as anti-convulsants

A class of tricyclic glycinamide derivatives is described having use in treatment of CNS dysfunctions such as epilepsy and convulsive disorders. Compounds of most interest are those of the formula wherein each of X and Y is hydrido; wherein Z is selected from methylene, ethylene, ethenylene, thiomet...

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Bibliographische Detailangaben
Hauptverfasser: CORDI, ALEXIS A, GILLET, CLAUDE L
Format: Patent
Sprache:eng
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Zusammenfassung:A class of tricyclic glycinamide derivatives is described having use in treatment of CNS dysfunctions such as epilepsy and convulsive disorders. Compounds of most interest are those of the formula wherein each of X and Y is hydrido; wherein Z is selected from methylene, ethylene, ethenylene, thiomethylene and thioethylene; and wherein each of R1, R2 and R3 is hydrido; or a pharmaceutically-acceptable salt thereof.