DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS
Novel compounds of the general formula I processes for its preparation, pharmaceutical compositions containing such compounds as the active ingredient and the use of the compounds in medicine, especially for use in inhibiting gastric acid secretion and in the treatment of gastrointestinal inflammato...
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creator | BRIVING CARIN B LINDBERG PER L CARLSSON STIG A. I MATTSSON ANNIE H NORDBERG MATS P WALLMARK BJOERN M. G |
description | Novel compounds of the general formula I processes for its preparation, pharmaceutical compositions containing such compounds as the active ingredient and the use of the compounds in medicine, especially for use in inhibiting gastric acid secretion and in the treatment of gastrointestinal inflammatory deseases. R represents aryl, cycloalkyl or an adamantyl group. R represents hydrogen, alkyl, alkoxy or halogen. R represents hydrogen, alkyl, phenalkyl or a cykloalkyl-alkyl group. R and R represents hydrogen or alkyl. R represents hydrogen, alkyl, aryl or a hydroxylgroup when n= 1-6 or an amino when n=O. A representents an alkylene, optionally connected to, or interrupted by an optionally substituted heteroatom selected from O,S and NR. n is 0-6. |
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R represents hydrogen, alkyl, phenalkyl or a cykloalkyl-alkyl group. R and R represents hydrogen or alkyl. R represents hydrogen, alkyl, aryl or a hydroxylgroup when n= 1-6 or an amino when n=O. A representents an alkylene, optionally connected to, or interrupted by an optionally substituted heteroatom selected from O,S and NR. n is 0-6.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS |
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