Quaternized PEI silica solid supports for chromatography

Quaternized non-crosslinked polyethyleneimine silica based solid supports are useful strong anion exchangers for column chromatography separation and purification of proteins and have high binding capacity at high pH, the ability to bind basic proteins having high pH isoelectric points and are rapid...

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Bibliographische Detailangaben
Hauptverfasser:	RAMSDEN, HUGH E, KAKODKAR, SUNIL V
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	Quaternized non-crosslinked polyethyleneimine silica based solid supports are useful strong anion exchangers for column chromatography separation and purification of proteins and have high binding capacity at high pH, the ability to bind basic proteins having high pH isoelectric points and are rapidly equilibrated and are essentially non-titratable.