2-(HETEROCYCLYLALKYL)IMIDAZOPYRIDINES

2-(HETEROCYCLYLALKYL)IMIDAZOPYRIDINES

Antiallergic 2-(heterocyclylalkyl)imidazopyridines of formula wherein -A =A -A =A - is -N=CH-CH=CH-, -CH=N-CH=CH-, -CH=CH-N=CH-, -CH=CH-CH=N-, -N=CH-N=CH- or -CH=N-CH=N-; R is hydrogen, C1-10alkyl, C3-6cycloalkyl, Ar , C1-6alkyl or a radical of formula -Alk-G-R ; R is hydrogen or C1-6alkyl; m is 1 t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JANSSENS, FRANS E, DIELS, GASTON S. M, SOMMEN, FRANCOIS M, TORREMANS, JOSEPH L. G
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Antiallergic 2-(heterocyclylalkyl)imidazopyridines of formula wherein -A =A -A =A - is -N=CH-CH=CH-, -CH=N-CH=CH-, -CH=CH-N=CH-, -CH=CH-CH=N-, -N=CH-N=CH- or -CH=N-CH=N-; R is hydrogen, C1-10alkyl, C3-6cycloalkyl, Ar , C1-6alkyl or a radical of formula -Alk-G-R ; R is hydrogen or C1-6alkyl; m is 1 to 4; n is 1 or 2; L is hydrogen, C1-6alkylcarbonyl, C1-6alkylsulfonyl, C1-6alkyloxycarbonyl, Ar -C1-6alkyloxycarbonyl, Ar -carbonyl, Ar -sulfonyl, C3-6cycloalkyl, C2-6alkenyl optionally substituted with Ar , C1-12alkyl, a radical of formula -Alk-R , -Alk-Y-R , Alk-Z -C(X)-Z -R or -CH2-CHOH-CH2-O-R ; the pharmaceutically acceptable acid addition salts and possible stereochemically isomeric forms thereof, novel compounds of formula (I); pharmaceutical compositions containing such compounds as an active ingredient and methods of preparing said compounds and pharmaceutical compositions.