Preparation of 99m Tc radiopharmaceuticals

PCT No. PCT/AU84/00268 Sec. 371 Date Aug. 23, 1985 Sec. 102(e) Date Aug. 23, 1985 PCT Filed Dec. 21, 1984 PCT Pub. No. WO85/03063 PCT Pub. Date Jul. 18, 1985.Compounds of the formula I: R+[99mTcNX4]-I wherein R+ represents a cation and X represents a halo group, are prepared by reaction with an azid...

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Hauptverfasser:	BONNYMAN, JOHN, BALDAS
Format:	Patent
Sprache:	eng
Schlagworte:	BLASTING CHEMISTRY COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSESC01D OR C01F FLUID HEATERS, e.g. WATER OR AIR HEATERS, HAVING HEATGENERATING MEANS, IN GENERAL HEATING HUMAN NECESSITIES HYGIENE INORGANIC CHEMISTRY LIGHTING MECHANICAL ENGINEERING MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OF STEAM GENERATION PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES RANGES STEAM BOILERS STEAM GENERATION VENTILATING WEAPONS
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Zusammenfassung:	PCT No. PCT/AU84/00268 Sec. 371 Date Aug. 23, 1985 Sec. 102(e) Date Aug. 23, 1985 PCT Filed Dec. 21, 1984 PCT Pub. No. WO85/03063 PCT Pub. Date Jul. 18, 1985.Compounds of the formula I: R+[99mTcNX4]-I wherein R+ represents a cation and X represents a halo group, are prepared by reaction with an azide compound in the presence of a hydrohalic acid. The compounds are useful in production of 99mTc-labelled radio- pharmaceuticals by reaction with ligands and monoclonal antibodies or antibody fractions.