Fungal resistance markers

A drug resistant strain of P.chrysogenum has said drug resistance conferred by heterologuns DNA, in particular a heterologous gene(s) under the control of a Penicillium control sequence(s). Drug resistance is especially to sulphonomides, or to trimethoprim or methotrexate by a gene derived from plas...

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Hauptverfasser: SANCHEZ, FLORENTINA S, CARRAMOLINO-FITERA, LAURA, SUSAN, VICTOR R, ORTEGA, AGUSTIN P. A
Format: Patent
Sprache:eng
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Zusammenfassung:A drug resistant strain of P.chrysogenum has said drug resistance conferred by heterologuns DNA, in particular a heterologous gene(s) under the control of a Penicillium control sequence(s). Drug resistance is especially to sulphonomides, or to trimethoprim or methotrexate by a gene derived from plasmid R388. A vector capable of conferring resistance to methotrexate or sulphonamide on P.chrysogenum, comprises at least one said resistance gene under the control of trpC controlling sequences.