Anthracycline derivatives having cytostatic activity

Anthracycline derivatives having cytostatic activity

The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I I wherein R1 is a CH3(CH2)n group with n=0 to 3, R2 is a hydrogen atom or a methyl group, R3 is a hydrogen atom, a methyl group or an acyl protective group, and R4 is a hydrogen atom or an acy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KOLAR, CENEK, KRAEMER, HANS P, PAAL, MICHAEL, HERMENTIN, PETER
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Beschreibung
Zusammenfassung:The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I I wherein R1 is a CH3(CH2)n group with n=0 to 3, R2 is a hydrogen atom or a methyl group, R3 is a hydrogen atom, a methyl group or an acyl protective group, and R4 is a hydrogen atom or an acyl protective group, and which are optionally in the form of a salt of an inorganic or organic acid, to a process for their preparation and to their use in pharmaceuticals.