Pheophorbide derivatives

Novel pheophoribide derivative of the general formula: (wherein Z is O or NH; n is an integer of 1 to 6; Y is NR min R sec or (wherein R min , R sec and R''' are the same or different and each represents a C1 to C4 lower alkyl group; and X is a halogen or organic acid ion); R1 is an e...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	KARASAWA, MICHITO, OTANI, TAKUZO, UCHIMOTO, MARI, AIZAWA, KATSUO, KAWABE, HIROFUMI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Novel pheophoribide derivative of the general formula: (wherein Z is O or NH; n is an integer of 1 to 6; Y is NR min R sec or (wherein R min , R sec and R''' are the same or different and each represents a C1 to C4 lower alkyl group; and X is a halogen or organic acid ion); R1 is an ethenyl group, C1 to C4 lower alkyl group or (wherein m is an integer of 0 to 6, R6 is H or a C1 to C4 lower alkyl group); R2 is CH3, CHO or CH2OH; either of R3 and R4 is H, with the other being OH, or both of them combine to represent =O; R5 is H or CO2CH3) are useful in photodynamic diagnosis and therapy of cancer tissues.