Antianginal plate for treating ischemic heart disease

An antianginal composition in the form of a plate is provided for treating ischemic heart disease and is comprised of a biologically soluble and resolvable film and an antianginal coronary vasodilating nitrate. This film is placed buccally on the gum or mouth mucosa for rapid arresting or prevention...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DAVYDOV, ANATOLY B, UTYAMYSHEV, RUSTAM I, KHROMOV, GENNADY L, BABAIAN, EDUARD A, METELITSA, VLADIMIR I, SAVVATEEV, KONSTANTIN L, NOVIKOVA, ELIZAVETA B, GERASIMOVA, GALINA A, VIKHERT, ANATOLY M, PIOTROVSKY, VLADIMIR K
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:An antianginal composition in the form of a plate is provided for treating ischemic heart disease and is comprised of a biologically soluble and resolvable film and an antianginal coronary vasodilating nitrate. This film is placed buccally on the gum or mouth mucosa for rapid arresting or prevention of angina pectoris attacks. The antianginal film is in the form of a plate, 0.1 to 1.5 mm thick, consisting of a biologically soluble and resolvable carrier. Preferably, the film is comprised of a homopolymer of acrylamide or vinylpyrrolidone, or a copolymer thereof with acrylate, containing from 99 to 70 percent by weight of acrylamide with vinylpyrrolidone and from 1 to 30 percent by weight of acrylate having a molecular mass from 50,000 to 1,000,000 and the active principle having antianginal action, the components being taken in the following proportions, in percent by weight: active substance having antianginal action: 3.0-30.0 biologically soluble and resolvable carrier: 70.0-97.