Reduction of carboxylic esters

A method for producing a compound of the formula: [wherein R and R each stand for a lower alkyl group; n denotes an integer of 0 to 21; X stands for hydrogen atom or an optionally protected hydroxyl group; and Y stands for an optionally protected hydroxyl group], which comprises by reducing an ester...

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Hauptverfasser: OKADA, TAIITI, ABE, YASUAKI
Format: Patent
Sprache:eng
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Zusammenfassung:A method for producing a compound of the formula: [wherein R and R each stand for a lower alkyl group; n denotes an integer of 0 to 21; X stands for hydrogen atom or an optionally protected hydroxyl group; and Y stands for an optionally protected hydroxyl group], which comprises by reducing an ester compound of the formula: [wherein R , R , n, X and Y are of the same meaning as defined above, and R stands for a lower alkyl group] with a mixture of sodium borohydride and aluminum chloride, gives the desired compound in a high yield, and is advantageous from the industrial point of view.