Protein absorption enhancing agents

A package containing (1) t-PA, (2) methylamine or a non-toxic salt thereof and (3) hydroxylamine or a non-toxic salt thereof, the amount of hydroxylamine or non-toxic salt thereof being sufficient to increase the absorption in the blood of the t-PA when it is administered non-intravascularly to a ma...

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Bibliographische Detailangaben
Hauptverfasser: SARNOFF, STANLEY, SOBEL, BURTON E
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A package containing (1) t-PA, (2) methylamine or a non-toxic salt thereof and (3) hydroxylamine or a non-toxic salt thereof, the amount of hydroxylamine or non-toxic salt thereof being sufficient to increase the absorption in the blood of the t-PA when it is administered non-intravascularly to a mammal and the amount of methylamine or non-toxic salt thereof being sufficient to reduce the amount of hydroxylamine or non-toxic salt thereof required to obtain the increased absorption of t-PA and a method for intramuscularly administering the same.