Quinoline derivatives

A process for preparing dihydro compounds of formula I, by rearranging compounds of formula II, e.g. in the presence of acids or noble metal catalysts, is described. The compounds II may be prepared from intermediates of formula III. I II III In these formulae R1,R2, R3, R4, R5, R6 and R7 are the sa...

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Bibliographische Detailangaben
Hauptverfasser: CROSSLEY, ROGER, HEATHERINGTON, KENNETH
Format: Patent
Sprache:eng
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Zusammenfassung:A process for preparing dihydro compounds of formula I, by rearranging compounds of formula II, e.g. in the presence of acids or noble metal catalysts, is described. The compounds II may be prepared from intermediates of formula III. I II III In these formulae R1,R2, R3, R4, R5, R6 and R7 are the same or different and represent hydrogen, or alkyl, cycloalkyl, aralkyl, or aryl radicals any of which radicals may be substituted, or R1 and R2 taken together or R2 and R3 taken together, form a 5, 6 or 7 membered ring which may be saturated or unsaturated and substituted or unsubstituted, R4 and R5 may also represent alkoxy, or cycloalkoxy, n is 1, 2 or 3 and, if more than one R4 radical is present the R4 radicals may be the same or different and R6 and R7 represent hydrogen, alkyl, cycloalkyl, or aralkyl radicals. Most of the compounds I, II and III are novel and are claimed. They are intermediates for anti-ulcer agents.