Dihydropyridine preparations containing beta -blockers

An antihypertensive and antianginal combination comprising (A) 0.1 to 10 parts by weight of an asymmetrical dihydropyridine of the formula in which R1 and R5 each independently is methyl, hydroxymethyl or cyano, R2 and R4 are always different from one another and each independently is alkyl with 1 to 10 carbon atoms optionally substituted by alkoxy with 1 to 4 carbon atoms, fluorine, chlorine or N-methyl-benzylamino, R3 is nitro, chlorine, trifluoromethyl, or =N-O-N=, and n is 1 or 2, and (B) about 10 to 200 parts by weight of a beta -blocker preferably without a local anesthetic action.