4H-benzo(4,5)cyclohepta(1,2-B)thiophene derivatives

4H-benzo(4,5)cyclohepta(1,2-B)thiophene derivatives

alpha -[5H-dibenzo[a,d]cyclohepten-5-ylidene]-carboxylic acids e.g. of formula I (I) wherein R1 is H, C1-4alkyl or phenyl-(C1-4alkyl), R2 is H or C1-4alkyl and ring A is unsubstituted or halo- or hydroxy-substituted, as well as the physiologically-hydrolysable and -acceptable esters thereof have val...

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Bibliographische Detailangaben
Hauptverfasser: BOLLINGER, PIETRO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:alpha -[5H-dibenzo[a,d]cyclohepten-5-ylidene]-carboxylic acids e.g. of formula I (I) wherein R1 is H, C1-4alkyl or phenyl-(C1-4alkyl), R2 is H or C1-4alkyl and ring A is unsubstituted or halo- or hydroxy-substituted, as well as the physiologically-hydrolysable and -acceptable esters thereof have valuable pharmaceutical, in particular anti-inflammatory, antipyretic and analgesic properties.