Anthracyclin derivatives

The present invention relates to anthracyclin derivatives of the formula I (I) in which R1 and R2 are identical or different and represent the sugar residue Roa (L-rhodosamine) of the formula or the sugar combination Roa-dF=CinB (dF=2-deoxy-L-fucose; CinB=L-cinerulose B) of the formula The invention...

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Hauptverfasser: BERSCHEID, HANS G, HUBER, GERHARD, FEHLHABER, HANS-WOLFRAM, KRAEMER, HANS P
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creator BERSCHEID
HANS G
HUBER
GERHARD
FEHLHABER
HANS-WOLFRAM
KRAEMER
HANS P
description The present invention relates to anthracyclin derivatives of the formula I (I) in which R1 and R2 are identical or different and represent the sugar residue Roa (L-rhodosamine) of the formula or the sugar combination Roa-dF=CinB (dF=2-deoxy-L-fucose; CinB=L-cinerulose B) of the formula The invention furthermore relates to a process for the preparation of the above compounds of the formula I, and to their use as cytostatic agents.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title Anthracyclin derivatives
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